Clinical queries

 

 

Interested in writing a Knowledge Summary?

Knowledge Summaries are like critically appriased topics; they answer a specific and focused clincal question by looking at the best available evidence.

The first step is to define your question. Either pick one of our clinical queries from the below categories, or write your own, then contact us stating your question. NB: It is vital that you contact us for approval of your clinical query before you proceed to write.

We will then help you with the next steps. For further information please see our Guidelines for authors.

 

Canine

  1. Answer Me: In dogs with neck pain due to intervertebral disc protrusion, are glucocorticoids superior to NSAIDs in providing analgesia?
  2. Answer Me: In dogs in status epilepticus, does application of benzodiazepines affect the prognosis as measured by mortality rate, when compared to post-seizure monitoring (may need example) alone?
  3. Answered: In Dogs With a European Adder Bite, Does the Use of Antivenom With Supportive Treatment Compared to Supportive Treatment Alone Improve Time to Recovery?
  4. Answer Me: In dogs with visceral pain, is Butorphanol more effective than Buprenorphine or Hydromorphone in providing analgesia?
  5. Answer Me: In dogs with infectious tracheobronchitis, does antimicrobial therapy decrease time to resolution of clinical signs, when compared to no treatment?
  6. Answered: Does Adding Transdermal Nitroglycerine to Other Therapies Used for Management of Left-sided Congestive Heart Failure in Dogs Speed the Resolution of Clinical Signs?
  7. Answered: In dogs with Methaldehyde intoxications, are benzodiazepines (such as diazepam or midazolam) more effective than Methocarbamol in reducing the severity and frequency of seizures?
  8. Answer Me: In dogs that have swallowed a foreign body, is endoscopy effective in removing the object, in comparison to surgery?
  9. Answer Me: In dogs with permethrin intoxication is Intralipid IVLE therapy or ClinOleic IVLE therapy more effective in reducing hospitalisation time?
  10. Being Answered: In dogs with an adder bite, does antibiotic intervention reduce the incidence of wound infection, when compared to no antibiotic intervention?
  11. Answer Me: In dogs with an adder bite, does the use of Penicillin (eg. Amoxicillin and Clavulanate) reduce the incidence of wound infection, when compared to cephalosporins?
  12. Answer Me: In male dogs does early castration (<1 year) when compared to unneutered dogs result in increased fearful and anxious behaviour?
  13. Answer Me: In dogs with a history of anal gland impaction does routine prophylactic emptying compared with no routine prophylactic emptying result in reduced incidence or frequency of anal gland impaction?
  14. Answer Me: In male dogs, is pre-pubertal neutering compared to post-pubertal neutering more effective ate reducing the incidence and/or severity of mounting behaviours?
  15. Answered: In dogs weighing under 15 Kg with unilateral cranial cruciate ligament disease does the tibial tuberosity advancement (TTA) technique lead to a better long-term functional outcome than the lateral fabellar suture (LFS) technique?
  16. Being Answered: In dogs with cranial cruciate ligament disease, is non-surgical treatment as effective as surgical treatment with lateral fabellar suture technique in reducing time to recovery?
  17. Being Answered: Does tibial tuberosity transposition and advancement or a modified TPLO procedure provide the best clinical outcome for dogs with cranial cruciate deficiency and concomitant medial patella luxation?
  18. Answered: In dogs with periodontal disease is feeding a complete raw meat diet more effective than a complete kibble 'dental' diet at reducing periodontal disease?
  19. Answer Me: In dogs with degenerative osteoarthritis is meloxicam superior to aspirin in improving standard lameness assessments e.g. canine brief pain inventory or similar?
  20. Being Answered: In dogs with nictitating gland prolapse (cherry eye) does gland removal increase the risk of keratoconjunctivitis sicca (dry eye) compared to gland replacement?
  21. Answer Me: In dogs with uncomplicated acute diarrhoea does metronidazole or bismuth subsalicylate result in faecal consistency (score) more rapidly returning to normal?
  22. Answer Me: In dogs with splenic neoplasia, does fine needle aspiration or needle core biopsy provide a more accurate diagnosis when compared to histology post splenectomy?
  23. Answer Me: In dogs with haemorrhagic gastroenteritis, does treatment with amoxicillin clavulanate compared to no treatment improve survival to discharge or reduce the period of hospitalisation?
  24. Answer Me: In dogs with gingivitis, does daily brushing with human (gingivitis specific) toothpaste, compared to regular canine toothpaste, ,have a greater effect to reduce the gingivitis score?
  25. Being Answered: In dogs with degenerative arthritis which gives the greatest improvement in pain scores - controlled exercise OR weight loss?
  26. Being Answered: In dogs with inflammatory enteropathy (idiopathic inflammatory bowel disease) is Budesonide more effective than prednisolone or prednisone in resolving clinical signs or improving the canine IBD activity index (CIBDAI) or the canine CE clinical activity index (CCECAI)?
  27. Answer Me: Do obese dogs (BCS ≤7) have more health problems than dogs of normal body weight (BCS 4 or 5) as assessed by the average number of non-routine yearly visits to their veterinary practice?
  28. Answer Me: In dogs with acute tracheobronchitis does treatment with theophylline versus trimethoprim-sulphonamide lead to a shorter time to cessation of coughing?
  29. Being Answered: In canine appendicular fractures, is low-level laser therapy (≤200mW) more effective than low-intensity pulsed ultrasound (≤30mW/cm2) in improving radiographic bone healing time?
  30. Answered: In adult dogs, does feeding a raw food diet alter urine composition compared to a kibble diet?
  31. Answered: In dogs with traumatic elbow luxation, does closed reduction and conservative management result in a better outcome than open reduction and surgical management?
  32. Answer Me: In dogs, does regular tooth brushing (> 3 times per week) reduce the rate of development of periodontal disease?
  33. Answer Me: In adult male dogs does castration under 1 year of age compared with castration at more than one year of age result in an increased risk of cranial cruciate ligament rupture?
  34. Answer Me: Are dogs managed medically with meloxicam for  thoracolumbar intervertebral disc disease at higher risk of developing gastritis compared to dogs managed with gabapentin?
  35. Being Answered: Does an egg-based oral rabies vaccination (ORV) intervention in stray dog populations result in greater uptake and more successful vaccination in a rabies control programme in South and South East Asian countries compared to other ORV baits? 
  36. Answer Me: In adult dogs does hair in the ear canals increase the risk of otitis externa compared to dogs with non-hairy ear canals?
  37. Being Answered: In birthing bitches undergoing a caesarean does premedication with methadone compared to post procedural analgesic negatively affect suckling behaviour?
  38. Answered: In anxious dogs does the use of pressure vests compared to no pressure vests reduce the signs of anxiety/fear?
  39. Answer Me: In dogs with generalised demodicosis, does the use of isooxazolines compared to a combined formulation of imidacloprid and moxidectin result in a similar rate and  level of reduction of clinical signs?
  40. Answer Me: In dogs does combining routine dental work with neutering result in more complications associated with neutering than dogs only being neutered?
  41. Answer Me: In dogs with acute haemorrhagic gastroenteritis, does the addition of antimicrobials to treatment with prebiotics result in a more rapid return to normal stool consistency than using prebiotics alone?
  42. Answered: In stressed dogs does the use of a Pet Remedy diffuser, compared to not using one, result in lowered levels of stress?
  43. Answered: In dogs suspected of having steroid responsive meningitis-arteritis (SRMA), how long should immunosuppressive monotherapy with steroids be undertaken in order to achieve clinical resolution without relapse of clinical signs?
  44. Answer Me: In dogs undergoing neutering surgery, following surgical hand scrubbing, does the additional use of sterile gloves lead to lower rates of post operative infection compared to scrubbing alone?
  45. Answer Me: In dogs undergoing abdominal surgery, is intravenous paracetamol given intra and post operatively as effective or better than tramadol with respect to severity of pain (pain score, eating, appetite)?
  46. Answer Me: In dogs does neutering compared to non-neutering reduce the risk of prostate problems?
  47. Being Answered: In dogs with osteoarthritis does grapiprant compared to no grapiprant result in a reduction in osteoarthritic pain?
  48. Answered: In greyhounds with recurring pedal corns, is wedge excision compared to repeatedly extirpating the corn more effective at resolving lameness?
  49. Answered: In neutered female dogs, what is the incidence of post-operative uterine pathology in ovariectomized bitches compared to ovariohysterectomized bitches?
  50. Answer Me: In dogs does neutering increase the risk of orthopaedic conditions when compared to unneutered dogs?
  51. Being Answered: In dogs with a mammary tumour undergoing surgery, what proportion will show evidence of metastasis with thoracic radiography compared to thoracic CT?
  52. Answer Me: In adult dogs, does long hair coat result in higher rectal temperatures following exercise compared to dogs with short (natural or clipped) coats?
  53. Answered: Is an anchoring or pocket technique best for surgical repair of cherry eye in dogs?
  54. Answered: Can the measurement of glucose levels in blood and peritoneal fluid, instead of cytology and bacterial culture of peritoneal fluid, be used to diagnose septic peritonitis in dogs?
  55. Answered: Is garlic (Allium sativum) efficacious as an anthelmintic to prevent or reduce the intestinal worm burden (species found in the UK) of dogs?
  56. Answered: In dogs with atopic dermatitis are antihistamines as effective as glucocorticoids at reducing the severity of the clinical signs?
  57. Being Answered: In dogs with chronic pain, does the use of acupuncture reduce pain compared with no treatment?
  58. Answer Me: In dogs with immune-mediated haemolytic anaemia, does the addition of mycophenolate mofetil to corticosteroids confer benefit compared with corticosteroids alone?
  59. Answer Me: In dogs with neurological dysfunction/post-ligation seizures post attenuation of PSS, is levetiracetam or a benzodiazepine preferred to phenobarbital?
  60. Answered: In dogs with chronic enteropathy that have hypocobalaminaemia, can oral tablets be used instead of injectable protocols?
  61. Answered: The use of ultrasonography for detection of meniscal damage in dogs.
  62. Being Answered: In dogs diagnosed with primary (unassociated) immune-mediated thrombocytopenia, does treatment with glucocorticoids combined with ciclosporin (or another specified immunosuppressive agent) result in a shorter hospitalisation period compared to treatment with glucocorticoids alone?
  63. Being Answered: In dogs that undergo ligation of patent ductus arteriosus (PDA), is there a difference in procedural complication rates when comparing surgical and interventional techniques?
  64. Answered: In dogs over 15kg with cranial cruciate ligament rupture, does treatment with TPLO result in a better outcome than placement of a lateral fabellotibial suture.
  65. Being Answered: Is an admission or pre-operative lactate level a reliable predictor of survival to discharge in dogs presenting with GDV?
  66. Answer Me: Does treatment with intravenous human immunoglobulin in addition to immunosuppressive therapy improve survival time in dogs with primary (unassociated) IMHA compared to those receiving immunosuppressive therapy alone?
  67. Answered: In dogs undergoing enterotomy or enterectomy surgery, does the use of monopolar diathermy to make the intestinal incision increase the risk of dehiscence of the intestinal closure when compared to using a scalpel blade for the same purpose?
  68. Being Answered: In dogs undergoing dental extractions, does the use of peri-operative (24 hours) systemic antimicrobial therapy compared to no antimicrobial use result in fewer post-operative systemic or local infections?
  69. Answered: In dogs with B-cell lymphoma, does the use of flow cytometry provide useful prognostic information?
  70. Answer Me: In dogs diagnosed with anal sac apocrine gland adenocarcinoma localised to the anal sac, following surgically removal does adjunctive chemotherapy improve median survival time?
  71. Being Answered: In canines diagnosed with osteoarthritis, is treatment with allogenic mesenchymal stem cell therapy, compared with a placebo, more efficacious at reducing lameness and pain?
  72. Answered: Does the occurrence of ventricular arrhythmia reduce the rate of survival compared to no cardiac arrhythmia in dogs with GDV?
  73. Answered: Scoping review - MSI shoulder instability
  74. Answer Me: In adult dogs with osteoarthritis, does the supplementation of omega-3 fatty acids in their daily diets reduce the severity of signs associated with osteoarthritis when compared with a normal diet without omega-3 fatty acid supplementation?
  75. Answer Me: In adult female dogs does neutering before the first season compared with neutering after the first season result in an increased risk of cranial cruciate ligament rupture?
  76. Answer Me: In dogs in acute anaphylaxis, does administration of intravenous methylprednisolone or dexamethasone improve survival to discharge compared to standard supportive treatment?
  77. Answered: Is there supportive evidence to use torasemide over furosemide as a first line diuretic in dogs with newly diagnosed congestive heart failure?
  78. Answered: In healthy dogs undergoing open wound management, does the topical application of honey result in faster rates of wound healing when compared with wounds that were not treated with topical honey?
  79. Being Answered: Are puppies fed a raw meat based diet versus a commercially formulated diet at greater risk of nutrient imbalance?
  80. Answer Me: In dogs with a surgical wound, does the use of laser >0.5 mW accelerate wound healing when compared to not using laser treatment?
  81. Being Answered: In spayed female dogs, does phenylpropanolamine as compared to oestrogen-based medications result in a reduced incidence rate of urinary incontinence?
  82. Answer Me: In dogs recovering from elective neutering does feeding a bland diet versus feeding usual diet reduce the incidence of post-operative complications, specifically gastro-intestinal upset?
  83. Answered: In Bitches Diagnosed with Pyometra, is Medical Therapy Using Antibiosis Alone as Effective as Combining Ovariohysterectomy with Antibiosis in Reducing Morbidity and Mortality?
  84. Answered: The Evidence Behind the Treatment of Canine Idiopathic Epilepsy
  85. Answered: The Evidence Behind the Diagnostic Investigation of Canine Idiopathic Epilepsy
  86. Answered: There is No Evidence For or Against the Use of Non-Steroidal Anti-Inflammatory Drugs to Reduce the Clinical Duration of Kennel Cough (Infectious Tracheobronchitis).
  87. Answered: Is Robenacoxib Superior to Meloxicam in Improving Patient Comfort in Dogs Diagnosed With a Degenerative Joint Process?
  88. Answered: Which is More Effective in Altering the Intra-Gastric pH in Dogs, Omeprazole or Ranitidine?
  89. Answered: No evidence that dogs affected by bicipital tenosynovitis treated surgically with tenotomy or tenodesis of the biceps tendon have a better outcome compared to conservative treated dogs
  90. Answered: Are Old Dogs Who Undergo Total Hip Replacement More Predisposed to Perioperative Femoral Fractures than Young Dogs?
  91. Answered: Are dogs that eat quickly more likely to develop a gastric dilation (+/- volvulus) than dogs that eat slowly?
  92. Answered: Are dogs fed from a raised bowl at an increased risk of gastric dilation volvulus compared with floor-fed dogs?
  93. Answered: Use of Lidocaine in Reducing Post-Operative Tracheitis in Dogs and Cats: A Knowledge Summary
  94. Answered: Are hydrolysed diets an effective means of reducing the gastro-intestinal symptoms in dogs with chronic enteropathy?
  95. Answered: In Dogs with Periodontal Disease Is Feeding a Complete Raw Meat Diet More Effective Than a Complete Kibble 'Dental' Diet at Reducing Periodontal Disease?
  96. Answered: In dogs with pyothorax does medical management result in comparable mortality to surgical management?
  97. Answered: Spaying of cats and dogs by laparoscopic ovariectomy may offer a more positive recovery than traditional open surgical methods
  98. Answered: Is alpha-casozepine efficacious at reducing anxiety in dogs?
  99. Answered: In Dοgs That Have Had Intussusception Is Enterοplication Efficient as an Additional Surgical Prοcedure in Preventing Subsequent Recurrence?
  100. Answered: Do palliative steroids prolong survival in dogs with multicentric lymphoma?
  101. Answered: Which sternotomy closure method (orthopaedic wire or suture) is recommended in large breed dogs undergoing a median sternotomy?
  102. Answered: Can cytosine arabinoside with prednisolone treatment for canine meningioencephalitis of unknown origin increase survival rate compared to prednisolone treatment alone?
  103. Answered: In dogs bitten by the European adder (Vipera berus), does treatment with corticosteroids and supportive treatment improve time to recovery compared to supportive treatment alone?
  104. Answered: Does the Use of Intratesticular Blocks in Dogs Undergoing Orchiectomies Serve as an Effective Adjunctive Analgesic?
  105. Answered: Is the use of hypertonic saline effective in reducing intracranial pressure after traumatic brain injury?
  106. Being Answered: In dogs with a displaced radial fracture, does the use of a free autologous greater omental graft combined with other standard fracture repair methods, compared to not using a greater omental graft, reduce fracture healing time?
  107. Answered: Are dogs fed a dry kibble - based diet more likely to experience an episode of gastric dilatation volvulus than dogs fed an alternative diet?
  108. Answered: In Adult Dogs, Is Feeding Enzyme-enriched Rawhide Products More Effective at Preventing Periodontal Disease from Developing Than Non-enriched Rawhide Products?
  109. Answer Me: On ovariohysterectomy, is there a higher incidence of uterine pathology in bitches that have had puppies compared to bitches neutered at a similar age that have not had puppies?
  110. Answered: In shelter-based dogs, does the use of an oral probiotic supplement, compared to no probiotic supplement, reduce the risk of diarrhoea developing?
  111. Answer Me: In dogs with osteoarthritis does oral treatment with turmeric compared to no treatment reduce the severity of the clinical signs?
  112. Being Answered: In dogs diagnosed with sinonasal aspergillosis, does the addition of debridement offer a better clinical outcome compared to dogs treated with a medical protocol alone?
  113. Answered: In bitches undergoing elective neutering via midline coeliotomy is ovariectomy superior to ovariohysterectomy in terms of anaesthetic duration, incision length and post-operative comfort?
  114. Answered: In dogs suffering from generalised demodicosis, is treatment with oral sarolaner more effective at resolving clinical signs compared to treatment with topical imidacloprid plus moxidectin?
  115. Answer Me: In dogs undergoing abdominal surgery, does the use of pre packaged swaged needles reduce the risk of post operative complications compared to manually threaded needles utilising suture material from a reel?
  116. Answer Me: In bitches with a pseudo-pregnancy, does neutering whilst clinical signs are still present lead to a higher incidence of persistence/recurrence compared to neutering when signs have resolved?
  117. Answered: In dogs with Cushing’s disease that are being treated with triolstane, does pre-trilostane measurement of cortisol levels provide better monitoring than ACTH stimulation tests?
  118. Answer Me: In bitches with urethral sphincter mechanism incompetence, does the placement of an artificial urethral sphincter compared to colposuspension result in a higher rate of resolution of clinical signs?
  119. Answered: In dogs with a surgical or open wound does low level laser therapy increase the speed of wound contracture and reduce the healing time?
  120. Being Answered: In anxious adult dogs is fluoxetine or clomipramine more effective in treating symptoms of fear and anxiety.
  121. Being Answered: In dogs undergoing surgical attenuation of congenital extrahepatic portosystemic shunts, does pre-treatment with Levetiracetam reduce the incidence of post-operative seizures
  122. Being Answered: In dogs suffering from degenerative lumbosacral stenosis, is surgical treatment more effective than medical therapy in reducing lower back pain and neurological dysfunction in the long-term?
  123. Answered: In dogs, is the oral administration of garlic, compared to no treatment, efficacious at preventing or reducing parasitism by fleas?
  124. Answered: In cats and dogs with traumatic diaphragmatic rupture, does surgical timing affect outcome?
  125. Answered: In dogs with aural haematoma does draining and injecting corticosteroids reduce the risk of recurrance compared to draining alone?
  126. Answer Me: In dogs with inflammatory airway disease, do corticosteroids compared with NSAIDs result in reduced frequency and severity of bronchoconstriction episodes?
  127. Answer Me: In bitches which have undergone a Caesarean section does oral medication with meloxicam increase the incidence of gastrointestinal side effects in the bitch or puppies when compared to non-NSAID analgesics?
  128. Answered: In dogs under going elective procedures using general anaesthesia does the use of mededtomidine during pre-medication result in an increase in anaesthetic complication rates when compared to the use of ACP as a premeditation
  129. Answered: Does Pheromone Base Therapy [PBT] reduce stress in dogs (Canis familiaris) in shelter environments?
  130. Answered: In healthy dogs, does the use of benzodiazepines in co-induction result in a reduction in the dose of propofol required to induce anaesthesia and a decrease in adverse cardiovascular and respiratory events?
  131. Being Answered: In growing dogs does restricting daily exercise to 5 minutes multiplied by the age in months reduce the risk of skeletal growth disorders when compared to higher levels of exercise?
  132. Answer Me: In bitches with placental retention following Caesarean section, does prophylactic antimicrobial therapy reduce the risk of uterine infection compared to no prophylactic antimicrobial treatment?
  133. Being Answered: In dogs affected by IMHA, does sequential measurements of C reactive protein to determine the time of reduction of immunosuppressive treatment compared to using stability of PCV (Haematocrit) lead to a lower total dose of immunosuppressive treatment given?
  134. Answered: In bitches undergoing cesarean section, is an alfaxalone induction as effective as a propofol induction?
  135. Answered: In dogs with [anorexia][vomiting] does ranitidine have any beneficial effects to gastro-intestinal motility?
  136. Answer Me: In dogs with degenerative osteoarthritis is laser treatment superior to NSAID treatment in reducing the severity of the clinical signs?
  137. Answered: In dogs diagnosed with osteoarthritis, is Meloxicam superior than Carprofen for reducing patient discomfort?
  138. Answered: Comparison of epidural morphine and buprenorphine for hindlimb orthopaedic surgery in dogs
  139. Answered: In dogs diagnosed with a cutaneous mast cell tumour and undergoing primary surgery, does the size of the surgical margin affect the probability of recurrence?
  140. Answered: Does prescribing meloxicam or carprofen reduce gastrointestinal side effects?
  141. Answer Me: In bitches that have undergone a caesarean section, does NSAID therapy for more than 24 hours reduce puppy survival rate compared to 24 hours or less?
  142. Answer Me: In dogs with a gastric torsion does gastroplexy versus no intervention reduce the risk of recurrence?
  143. Answered: In bitches is an ovarectomy/ovariohysterectomy by laparoscopy superior to an ovarectomy/ovariohysterectomy by a mid-line surgical laparotomy in reducing post-operative pain?
  144. Answered: In adult dogs with naturally occurring medial meniscal tears concurrent to cruciate ligament disease, is meniscal release equal to or superior to meniscal resection in improving lameness?
  145. Answer Me: In large or giant dogs with gastric dilation (bloat), does injectable ranitidine compared with no treatment result in  a reduced risk of progression to gastric dilatation volvulus?
  146. Answered: In pregnant bitches, does an elective caesarean section compared to vaginal delivery reduce puppy mortality rates?
  147. Answered: The Pre-incisional block with bupivacaine: Is there any effect on analgesia following celiotomy in dogs?
  148. Answered: In dogs undergoing anaesthesia does pre-anaesthetic gastro-protectants vs no gastro-protectants reduce gastro-oesophageal reflux (GOR)?
  149. Answered: In routine canine caesareans, is alfaxalone a superior anaesthetic induction agent than propofol in increasing the rate of survival and vigour of neonates
  150. Answer Me: In canine patients recovering from spinal surgery for intervertebral disc extrusion, does the implementation of passive range of motion (PROM) exercises, compared to not implementing PROM, lead to a quicker recovery?
  151. Answer Me: In dogs with degenerative osteoarthritis does tramadol hydrochloride provide comparative or superior analgesia when compared with meloxicam?
  152. Answer Me: In dogs with urothelial carcinoma does carboplatin or mitoxantrone with a COX-2 inhibitor compared to a COX-2 inhibitor alone result in increased survival time? 
  153. Being Answered: In diabetic dogs with ketoacidosis, that requires fluid therapy, does 0.9% saline result in inferior/similar/superior outcomes when compared to  a buffered crystalloid such as Hartman's solution?
  154. Answered: In adult domestic dogs, does the exposure to dog-appeasing pheromones reduce the frequency of occurrence and/or severity of anxiety-related behaviours when compared to no exposure.
  155. Answer Me: In dogs requiring analgesia, does supplementation of NSAIDs with maropitant reduce the severity of pain compared to NSAIDS alone?
  156. Answered: What is the specificity and sensitivity of cytology as a test for canine osteosarcoma when compared to histopathology as a gold standard?
  157. Being Answered: In dogs with corneal ulcers accompanied by melting keratitis, does intraocular application of patient serum in addition to antimicrobial drops result in a reduced need for surgical intervention compared to antimicrobial drops alone?
  158. Out of radiography and CT what is the best way to diagnose radioulnar incongruence in dogs?
  159. Answered: In dogs with uncomplicated corneal ulcers does prophylactic antibiotic eye drops reduce the risk of secondary infection when compared to no prophylactic antibiotic drops?
  160. Answered: Does surgical or medical management of extrahepatic portosystemic shunts in dogs carry a better prognosis for the resolution and reduction of neurologic dysfunction?
  161. Answered: Do dogs with cranial cruciate ligament disease managed non-surgically have better outcomes with rehabilitation?
  162. Answered: In dogs with atopic skin disease, is lokivetmab more effective in reducing the canine atopic dermatitis lesion index (or some other recognised scoring system) than oclacitinib?
  163. Being Answered: In dogs with congenital intrahepatic portosystemic shunts treated with suture ligation are the outcomes inferior/equivalent/superior when compared to treatment with transvenous coil embolism?
  164. Being Answered: In dogs, is toothbrushing more effective at reducing the onset and severity of dental disease than provision of dental chews?
  165. Answered: In dogs with osteoarthritis how effective is treatment with tramadol in reducing the severity of the clinical signs associated with pain when compared to no treatment?
  166. Answered: In canine lymphoma, does the supplement of turkey tail (Trametes versicolor) as an adjuvant therapy lead to a better quality of life than those that do not?
  167. Being Answered: In adult dogs under general anaesthesia what is the shortest period of pre-anaethesia fasting that will minimise the risk of gastroesophageal reflux, regurgitation and emesis during anaesthesia?
  168. Being Answered: In dogs diagnosed with gastric dilatation-volvulus (GDV), does gastric decompression and gastropexy reduce the risk of recurrence of GDV compared to dogs undergoing gastric decompression alone?
  169. Answered: Does medical or surgical treatment for aortic stenosis improve outcome in dogs?
  170. Answer Me: In dogs with urothelial carcinoma does piroxicam or meloxicam treatment result in increased survival time compared to no treatment? 
  171. Being Answered: In bitches, does neutering versus non-neutering reduce the risk of mammary tumours?
  172. Answered: Evaluating the reliability of computed tomography for the diagnosis of intervertebral disc extrusion in dogs
  173. Answered: Are dogs with hip dysplasia less painful with total hip replacement than femoral head ostectomy?
  174. Answered: Mortality rate comparison of enterotomy and resection and anastomosis in dogs with foreign body obstructions
  175. Answered: Should we prescribe metronidazole or probiotics for acute gastroenteritis in dogs?
  176. Answer Me: Cavitation as a predictor of malignancy in canine splenic masses
  177. Answered: Uncomplicated gallbladder mucoceles – is it better for prognosis to perform cholecystectomy or medically manage?
  178. Being Answered: In canine patients displaying signs of nausea and vomiting is maropitant administered parenterally compared with metoclopramide administered parentally more effective at reducing the frequency and severity of clinical signs?
  179. Answered: Comparison of marine-based omega-3 fatty acids as an adjunct to NSAID vs NSAID therapy alone in the peak vertical force exerted by affected limb(s) of osteoarthritic dogs
  180. Answer Me: In adult dogs with situational anxiety does clonidine or trazodone more effectively reduce signs of anxiety
  181. Being Answered: In dogs diagnosed with elbow dysplasia, does arthroscopic surgical intervention compared with conservative management result in improved mobility and reduced pain?
  182. Answered: Current evidence supporting simultaneous prophylactic gastropexy in canine patients undergoing complete splenectomy
  183. Answered: B.burgdorferi Exposure in Coyotes: an indicator of B.burgdorferi levels in urban versus rural environments
  184. Answered: The use of metronidazole in adult dogs with acute onset, uncomplicated, diarrhoea
  185. Answer Me: In dogs with acute pancreatitis, does enteral nutrition compared to parenteral nutrition result in fewer complications?
  186. Being Answered: In dogs undergoing epidurals, does ropivacaine or bupivacaine provide a longer lumbosacral sensory block and speed of motor function return?
  187. Being Answered: In primary (unassociated) immune-mediated thrombocytopaenia in dogs, is platelet function altered following the use of vincristine compared to before vincristine was administered?
  188. Answered: In dogs is IDEXX Angio Detect™ a more accurate test than either Baermann coprology or Angiostrongylus vasorum antigen ELISA when diagnosing Angiostrongylus vasorum infection?
  189. Answered: When treating medial patellar luxation grade II-III in small breed dogs, is a block recession trochleoplasty superior to a wedge recession trochleoplasty?
  190. Being Answered: In dogs and cats, is taking an axillary temperature comparably accurate to a rectal temperature?
  191. Being Answered: In dogs undergoing anaesthesia, does the use of trazodone reduce injectable or inhalant anaesthetic agent administration?
  192. Being Answered: In hospitalised dogs or dogs confined post-surgery, does administration of trazodone reduce stress related behaviours compared to no treatment with trazodone?
  193. Being Answered: In canine soft tissue sarcomas, what is the diagnostic accuracy of cytology compared to histopathology?
  194. Being Answered: Does use of selective serotonin-reuptake inhibitors reduce the severity of anxiety-related conditions in companion dogs at least 8 months of age when compared with no treatment?
  195. Answer Me: In Dogs With Snake Bites, Does the Use of the Antihistamine Diphenhydramine Compared to Not Using Diphenhydramine Reduce Mortality?
  196. Being Answered: In dogs, how accurate is abdominal ultrasound in detecting round cell neoplasia in the liver and spleen when compared to cytological or histopathological diagnosis?
  197. Being Answered: In male dogs undergoing surgical castration, does a pre-scrotal approach in comparison to a scrotal approach lead to a superior recovery, in terms of duration of post-operative pain and/or reduced post-operative complications?
  198. Being Answered: In Brachycephalic dogs undergoing surgery, does the administration of protein pump inhibitor drugs as part of the anaesthetic protocol reduce the incidence of regurgitation during or after anaesthesia when compared to no protein pump inhibitor drugs?
  199. Answer Me: In dogs who have undergone surgery for extrahepatic portosystemic shunt, is medical management an effective for treatment of seizures after shunt ligation?
  200. Being Answered: Do adult dogs that are brachycephalic have an increased risk for developing heatstroke compared to non-brachycephalic dogs?
  201. Answer Me: Are adult dogs on long term, legume rich, grain free diets more likely to be taurine deficient when compared to dogs fed on grain-based diets?
  202. Answer Me: In adult dogs with a cutaneous mast cell tumour does medical treatment with tiganol tiglate 1mg/ml (Stelfonta, Virbac) result in increased post treatment adverse events when compared with surgical treatment by local excision?
  203. Answer Me: Do dogs who are fed on a grain-free diet compared to a grain-based diet have an increased risk of dilated cardiomyopathy?
  204. Answer Me: In recumbent canine patients, does turning every 4 hours, compared with not turning the patient, reduce the impact of lung atelectasis?
  205. Being Answered: In dogs diagnosed with osteoarthritis, is treatment with an intra-articular injection of platelet-rich plasma reduce pain, compared with a placebo, more efficacious at reducing pain and lameness?
  206. Being Answered: In French Bulldogs diagnosed with intervertebral disk disease and reduced or absent proprioception, is hemileminectomy more effective than conversative treatment with NSAIDs +/- other analgesics and confinement?
  207. Being Answered: In dogs diagnosed with osteoarthritis (OA) how safe and effective is treatment with bedinvetmab, when compared to a placebo, in long-term reduction of the severity of the clinical signs associated with OA pain?
  208. Being Answered: In dogs with type I immune-mediated polyarthritis, is treatment with other immunosuppressive agents as effective as treatment with corticosteroids at reducing clinical signs?
  209. Being Answered: In dogs, does the use of chlorhexidine versus salt water or cooled boiled water to clean fresh skin wounds by owners increase the risk of delayed wound healing due to cytotoxicity?
  210. Answer Me: Does Maropitant have a superior anti-emetic efficacy than Metoclopramide when treating dogs with parvoviral enteritis-induced emesis?
  211. Being answered: In dogs with atopic skin disease, is lokivetmab more effective at reducing Canine Atopic Dermatitis Extent and Severity Index (CADESI)-3 score than ciclosporin?
  212. Being answered: Are adult dogs being fed a high-fat diet (>20%) more predisposed to pancreatitis compared to those fed a moderate-fat (10-15%) or low-fat (<10%) diet?
  213. Being answered: In dogs with transitional cell (urothelial) carcinoma undergoing ultrasound guided fine needle aspirate of the mass, what is the risk of tumour seeding along the needle tract?
  214. Being answered: In dogs with severe proteinuria, does telmisartan reduce the magnitude of the proteinuria more effectively than benazepril?

Equine

  1. Answered: In horses with superficial digital tendonitis is bandaging and rest compared to rest alone more effective at promoting healing?
  2. Answered: In horses with heel bulb lacerations, does casting the distal limb compared to bandaging result in faster healing?
  3. Answer Me: In horses are breast-strap harnesses more effective than breast-collar straps in preventing wounds?
  4. Answered: In lame horses affected by osteoarthritis of the distal tarsal joints (bone spavin), are bisphosphonates more effective than NSAIDs in long-term alleviation of lameness?
  5. Answered: In horses that are lame due to osteoarthritis of the distal tarsal joints (bone spavin), is intra-articular medication with corticosteroids compared to systemic bisphosphonate treatment more effective in long-term lameness reduction?
  6. Answered: In three day event horses, does biannual routine influenza vaccination compared to annual routine influenza vaccination reduce performance levels?
  7. Answered: Is removal of proximo-plantar osteochondral fragments necessary in young Thoroughbreds?
  8. Being Answered: In adult horses with superficial digital flexor tendonitis, does icing the leg in addition to non-steoidal anti-inflammatory therapy compared to non-steroidal anti-inflammatory treatment alone speed the healing process?
  9. Being Answered: In adult horses, is administering the live attenuated intranasal equine strangles vaccine alongside proper biosecurity compared to biosecurity measures alone (such as isolation), more effective in regards to the prevention of contracting equine strangles?
  10. Answered: In horses with arthritis, does the treatment with intra-articular anti-microbials concurrently with intra-articular corticosteroids reduce the risk of sepsis compared to intra-articular cortico-steroids alone?
  11. Answered: In Adult Horses With Septic Peritonitis, Does Peritoneal Lavage Combined With Antibiotic Therapy Compared to Antibiotic Therapy Alone Improve Survival Rates?
  12. Answered: In horses with chronic laminitis, do venograms compared to plain radiographs give greater diagnostic or prognostic information?
  13. Answered: In horses with allergen-related Recurrent Airway Obstruction (RAO), is immunotherapy compared to environmental reduction of allergen exposure more effective in disease modification?
  14. Answered: In Broodmares with post-service endometritis, is antibiotic intervention with other routine therapies superior to other routine therapies without antibiotic intervention in increasing pregnancy rate?
  15. Answer Me: In three day event horses, do bit seats compared to no bit seats improve performance?
  16. Answer Me: In Broodmares with Klebsiella-positive clitoral swabs, does the use of (specify antimicrobial) compared to transfaunation result in higher rates of resolution of colonisation?
  17. Answered: In horses with longitudinal tears of the deep digital flexor tendon, is surgical repair as effective as tenoscopic debridement alone for returning to previous level of performance?
  18. Answered: Do modern, oral/minimally invasive cheek tooth extraction techniques reduce the incidence of post-operative complications in the horse when compared to traditional repulsion methods?
  19. Answered: In horses with arthritis, does the treatment with intra-articular anti-microbials concurrently with intra-articular corticosteroids reduce the risk of sepsis compared to intra-articular cortico-steroids alone?
  20. Answered: No Evidence That Therapeutic Systemic Corticosteroid Administration is Associated With Laminitis in Adult horses Without Underlying Endocrine or Severe Systemic Disease
  21. Answered: Evidence supporting intralesional stem cell therapy to improve equine flexor tendon healing
  22. Answered: In an adult horse with severe asthma (RAO) does using inhaled corticosteroids result in an equal improvement in clinical signs when compared to systemic corticosteroids?
  23. Answered: Can Hoof Wall Temperature And Digital Pulse Pressure Be Used As Sensitive Non-Invasive Diagnostic Indicators Of Acute Laminitis Onset?
  24. Answered: In mares with placentitis does treatment with long term antibiotics result in improved outcome when compared to short course pulse antibiotic therapy of 7 to 14 days?
  25. Answered: In equids affected by acute laminitis, does continuous digital hypotermia of the lower limbs and supportive treatment improve clinical outcome compared to supportive treatment alone?
  26. Being Answered: In lame horses, caused by osseous cyst-like lesions in the proximal hindlimb, is box rest and analgesia administration more effective at returning the horse to previous level of performance in comparison to arthroscopic debridement?
  27. Being Answered: In acute colic admissions, can measuring serum amyloid A concentration accurately differentiate between medical and surgical cases?
  28. Answered: In horses with osteoarthritis, is mesenchymal stem cell therapy more effective at managing lameness than intra-articular corticosteroids?
  29. Answered: In horses undergoing volatile anaesthesia with isoflurane or sevoflurane, does administration of an alpha-2 agonist as a CRI compared to anaesthetic maintenance with volatile alone improve recovery quality?
  30. Answered: In horses with osteoarthritis is treatment with intra-articular polyacrylamide more likely to reduce the severity of clinical signs associated with lameness when compared to treatment with intra-articular corticosteroid?
  31. Answered: In horses with trigeminal-mediated headshaking, is neuromodulation with EquiPENS™ more effective than with electroacupuncture?
  32. Answered: In horses undergoing general anaesthesia, does assistance with ropes result in better recoveries when compared to no assistance ('free' recovery)?
  33. Answer Me: In horses with palmar foot pain, are eggbar shoes more effective than well-balanced traditional shoes in promoting longer-term soundness?
  34. Answered: In adult horses with secondary sinusitis, caused by dental disease, is computed tomography more accurate than radiography for the diagnosis of apical dental pathology?
  35. Answered: Can sedation be used for equine lameness investigation?
  36. Answer Me: In horses affected by Equine Herpesvirus Myeloencephalitis, does the administration of acyclovir or its prodrug valacyclovir reduce disease severity compared to alternative treatment?
  37. Being Answered: In horses that underwent exploratory coeliotomy, is an abdominal bandage associated with fewer incisional complications compared to no abdominal bandage?
  38. Answered: In horses with acute laminitis, does cryotherapy of the distal limbs applied after onset of clinical signs lead to improved clinical outcomes compared to horses treated without cryotherapy?
  39. Answer Me: In breeding mares that have undergone vernal transition, is the use of a recognised ovulation inducing agent more likely to result in ovarian follicular development or ovulation of a steroidogenically competent follicle more than 35 mm in diameter following a sequence of a few cold and or wet days in spring compared to following a sequence of warm and sunny days; or days that are not considered to be cold and or wet?
  40. Being Answered: In horses with lameness caused by navicular disease / syndrome, are bisphosphonates more effective than NSAIDs in long-term alleviation of lameness?
  41. Answer Me: In horses receiving allogenic blood transfusions, does receiving a cross-match and blood type compatible transfusion as compared to receiving a cross-match and blood type incompatible transfusion increase the survival time of erythrocytes?
  42. Answer Me: In horses receiving allogenic blood transfusions, does receiving a cross-match and blood type compatible transfusion as compared to receiving a cross-match and blood type incompatible transfusion reduce the incidence of transfusion reactions?
  43. Being Answered: In horses diagnosed with chronic injury of the proximal suspensory ligament, is conservative management combined with extra corporeal shockwave therapy (ECSWT) compared to conservative management alone more effective in long-term lameness reduction?
  44. Being Answered: In horses with navicular disease/syndrome, is barefoot more effective than remedial shoeing in long term alleviation of lameness?
  45. Being Answered: In horses undergoing volatile anaesthesia, is recovery quality superior with the use of isoflurane or sevoflurane?
  46. Being Answered: In horses with a suspensory ligament branch injury, does high-intensity laser therapy (energy output greater than 500 mW) combined with conservative management, compared to conservative management alone, result in a faster return to primary function?
  47. Being Answered: In horses with a kick wound to the medial aspect of the radius, is clinical suspicion of radial fracture always warranted?
  48. Answer Me: In horses with sarcoids undergoing treatment, does laser surgical excision compared to treatment with topical medication decrease rate of recurrence?
  49. Being Answered: In horses with flexor tendon lesions, does Platelet-Rich Plasma treatment lead to improved short-term outcomes compared to controlled exercise program?
  50. Being Answered: In adult horses with diagnosed overriding or impinging dorsal spinous processes, does medical management or surgical intervention provide a better outcome for return to previous work?

Exotics

  1. Answer Me: In a wild population of koalas infected with Chlamydia pecorum, will vaccination with a rMOMP vaccine decrease the severity of shedding and clinical disease in vaccinated animals compared to un-vaccinated animals?
  2. Being Answered: In avian surgery for repair of traumatic wounds is there a lower rate of post-operative complications when using polydioxanone as compared to poliglecapron 25 for closing the skin layer?
  3. TBC
  4. Being Answered: Is there a correlation between vaginal cytology (anuclear superficial epithelial cells) and estrus behaviour (calling, rolling, sniffing, grooming, scent marking) in the captive cheetah (Acinonyx jabutus) that will allow adequate captive management decisions on timing of natural mating and / or artificial insemination?
  5. Being Answered: In sea turtles presenting for sustained hypothermia (cold stunning), what blood analytes routinely evaluated at intake provide the most prognostic value?

Feline

  1. Answer Me: In healthy adult cats, does feeding commercial grain-free kibble compared to a generic adult formula kibble result in increased risk of hyperthyroidism?
  2. Answered: Are Adult Cats Fed on Wet Maintenance Diets Less at Risk of Developing Chronic Kidney Disease Compared to Adult Cats Fed on Dry Maintenance Diets?
  3. Answered: In cats with idiopathic Feline lower urinary tract disease (FLUTD), is prednisolone more effective than NSAIDs in reducing clinical signs?
  4. TBC
  5. Answer Me: In cats, does a canned-food diet reduce the risk of developing a UTI, when compared to dry diets?
  6. Answer me: In adult cats, does being obese (BCS >7/9) compared with being a healthy bodyweight (BCS 4-5/9) increase the incidence or severity of periodontal disease?
  7. Answered: In adult cats, does feeding grain free maintenance diet reduce the risk of obesity compared to feeding a maintenance diet containing grains?
  8. TBC
  9. TBC
  10. Answer Me: In adult cats does being obese (BCS >7/9) compared with being a healthy bodyweight (BCS 4-5/9) result in reduced longevity?
  11. Answer Me: In cats with renal secondary hyperparathyroidism, does the use of calcitriol in addition to dietary modification extend survival time compared to dietary modification alone?
  12. Answer Me: In kittens does being hand-reared compared with being naturally reared by the queen result in an increased lifetime likelihood of chronic gastrointestinal disease? 
  13. TBC
  14. Being Answered: In clinically hyperthyroid cats, is I-131 treatment superior to unilateral or bilateral thyroidectomy in normalising serum T4 level?
  15. Being Answered: In cats ≤10 years old, does the presence of degenerative osteoarthritis increase the likelihood of the cat being overweight (BCS ≥7) compared to cats that do not have osteoarthritis?
  16. Answer Me: In cats with self-barbering, does feeding a hypoallergenic diet improve clinical signs (measured through skin examination) compared to normal feeding?
  17. Answer Me: In cats with chin acne, does the topical use of benzoyl result in more rapid and sustainable resolution compared to no treatments?
  18. Answer Me: In cats with chin acne, does the use of corticosteroids result in more rapid and sustainable resolution than the use of antimicrobial treatments?
  19. TBC
  20. Answer Me: In cats with cystitis, is combined treatment with antibiotics and analgesia or treatment with analgesia alone more effective at resolving clinical signs?
  21. Answer Me: In adult cats, is honey effective in improving the healing of skin wounds, when compared to pharmaceutical topical treatments?
  22. Answer Me: In cats with traumatic brain injury, does the use of hypertonic saline compared to mannitol result in better neurologic recovery or higher survival rates?
  23. Answered: In cats with psychogenic alopecia, is over-grooming reduced by the use of clomipramine compared to untreated cats?
  24. Answered: In adult cats with lower urinary tract disease, is behavioural management more effective than drug management in reducing the risk of relapse?
  25. Answer Me: In adult male cats with urethrospasm causing obstruction, is indwelling catheterisation more effective than percutaneous drainage in reducing the likelihood of recurrence in the short term?
  26. Answer Me: In cats with traumatic brain injury, does the use of hypertonic saline compared to lactated Ringers solution result in better neurologic recovery or higher survival rates?
  27. Answer Me: In cats with metaldehyde intoxications, are benzodiazepines (such as diazepam or midazolam) more effective than methocarbamol in reducing occurrence of seizures?
  28. TBC
  29. TBC
  30. Answer Me: In cats undergoing surgical procedures that require aseptic skin preparation does the use of povidone iodine solutions of  ≥5% result in an increase risk of complications compared to using povidone iodine solutions of ≤1%?
  31. Being Answered: Does the use of a commercial FIV vaccine lead to effective prevention from the infection under field conditions in domestic cats, compared to not vaccinating?
  32. Answered: In cats which are stressed as a result of veterinary interventions does treatment with gabapentin lower the stress level compared to no treatment?
  33. Answer Me: Does clonality testing by PCR for antigen receptor rearrangement (PARR) aid differentiation of feline inflammatory bowel disease and alimentary lymphoma in equivocal cases?
  34. Being Answered: In cats with systemic arterial hypertension are there alternative anti-hypertensive drugs to amlodipine that are of equal or greater efficacy and safety profile for use?
  35. Answered: Is garlic (Allium sativum) efficacious as an anthelmintic to prevent or reduce the intestinal worm burden (species found in the UK) of cats?
  36. Answered: Do environmental changes prevent recurrence of episodes of feline Idiopathic Cystitis more effectively than medications?
  37. Answered: Feline Hyperthyroidism - Is dietary management within our reach?
  38. Answered: Of cats that present with aortic thromboembolism, do patients that receive thrombolytic therapy vs those who do not, have improved survival in the acute period?
  39. Answered: In adult cats with epilepsy which is poorly controlled with phenobarbital therapy alone, is imepitoin or levetiracetam more effective as a second-line anti-convulsant in order to reduce seizure frequency?
  40. Being Answered: In cats with cardiac disease, is treatment with clopidogrel associated with a reduced risk of arterial thromboembolism when compare to treatment with aspirin?
  41. Answer Me: In cats with chronic bronchitis, does the use of NSAIDS reduce the severity of the respiratory signs when compared to no intervention?
  42. Answered: Use of Lidocaine in Reducing Post-Operative Tracheitis in Dogs and cats: A Knowledge Summary
  43. Answered: Which Antibacterial Agent Performs Best for the Treatment and Clearance of Chlamydophila Felis Infection in cats?
  44. Answered: Spaying of cats and dogs by laparoscopic ovariectomy may offer a more positive recovery than traditional open surgical methods
  45. Answered: In cats infected with feline herpesvirus type-1 (FHV-1) does treatment with famciclovir result in a reduction of respiratory and ocular clinical signs?
  46. Answered: Is topical or systemic antimicrobial therapy more effective for the treatment of feline acne with secondary bacterial infection?
  47. Answered: Does the Use of Intratesticular Blocks in cats Undergoing Orchiectomies Serve as an Effective Adjunctive Analgesic?
  48. Answered: Percutaneous management of urethral blockages in cats
  49. Answered: Reluxation rates following different techniques for open stabilisation of feline coxofemoral dislocations
  50. Answered: In cats with feline interstitial cystitis does the use of meloxicam increase the speed of resolution of clinical signs compared to prednisolone?
  51. Answer Me: In cats with chin acne, does the use of systemic antimicrobials result in more rapid and sustainable resolution than the use of topical antimicrobial treatments?
  52. Answer Me: In cats with hyperthyroidism, does performing a bilateral staged thyroidectomy, compared to a simultaneous bilateral thyroidectomy, decrease the risk and/or severity of postoperative hypocalcaemia?
  53. Being Answered: Are tigers which are anaesthetised using a combination of tiletamine and zolazepam at greater risk of complications when compared to other anaesthetic agents?
  54. Answered: Is the new recommended standard flow rate of 3mL/kg/hour for cats and 5mL/kg/hour for dogs for surgical fluid therapy superior to previous recommended flow rate of 10mL/kg/hour for both cats and dogs?
  55. Answered: In cats infected with Tritrichomonas foetus does treatment with ronidazole result in successful eradication of infection?
  56. Answered: In cats and dogs with traumatic diaphragmatic rupture, does surgical timing affect outcome?
  57. Being Answered: in cats with chronic kidney disease is creatinine or SDMA a better biomarker for measuring glomerular filtration rate in cats with chronic kidney disease?
  58. Answer Me: In adult cats with inflammatory airway disease, does the use of cyproheptadine alone reduce the severity of associated clinical signs compared to no treatment?
  59. Being Answered: In cats within a clinical veterinary context, does the application of feline facial pheromone (Feliway™), when compared to placebo, reduce signs of acute stress?
  60. Being Answered: In cats with IRIS Stage 1 chronic kidney disease (CKD), does feeding a phosphate restricted versus standard adult cat food slow progression of CKD?
  61. Being Answered: In cats with proteinuric CKD (UPC > 0.4) does use of RAAS suppressing medication (benazepril or telmisartan) versus no intervention improve quality and/or length of life?
  62. Answer Me: In cats with IRIS Stage 1 chronic kidney disease (CKD), does feeding a phosphate restricted versus standard adult cat food slow progression of CKD?
  63. Answered: In a transfusion naïve cat is crossmatching recommended prior to the administration of type specific blood?
  64. Answered: In cats infected with papillomavirus is the risk of developing feline cutaneous squamous cell carcinoma greater than cat which are not infected with papillomavirus?
  65. Answered: Should we offer total hip replacement to feline patients?
  66. Being Answered: In symptomatic cats with feline immunodeficiency virus, does high-dose subcutaneous recombinant feline interferon omega administration combined with supportive therapy lead to reduced clinical signs compared to supportive therapy alone?
  67. Answer Me: In diabetic cats with ketoacidosis, that requires fluid therapy, does 0.9% saline result in inferior/similar/superior outcomes when compared to a buffered crystalloid such as Hartman's solution?
  68. Answered: In adults cats undergoing a venepuncture procedure, does the application of a topical lidocaine-based anaesthetic to the skin at the venepuncture site reduce the severity of the clinical signs associated with pain when compared to no topical anaesthetic?
  69. Answered: In cats with diabetes mellitus, does treatment with Protamine Zinc Insulin (PZI) have an inferior/equivalent/superior effect on the the severity of the clinical signs and the fequency hypoglycaemic episodes when compared compared to treatment with glargine (iGlar)?
  70. Answered: In cats with feline infectious peritonitis, does treatment with nucleoside analogs or protease inhibitors, compared to supportive measures alone, lead to longer survival times?
  71. Answer Me: Prazosin versus phenoxybenzamine in preventing recurrence of idiopathic urinary obstruction in cats
  72. Answered: Use of feline interdigital semiochemical (FIS) to redirect unwanted scratching behaviour in cats
  73. Being Answered: In cats with chronic bronchospasm and airway hypersensitivity (asthma) do oral glucocorticoids or inhaled glucocorticoids more effectively control clinical signs?
  74. Being Answered: In cats with anxiety, does pre-appointment trazodone administration, as compared to no trazodone, effectively reduce patients’ stress during veterinary visit?
  75. Being Answered: In cats with chronic kidney disease (CKD), requiring analgesia, does meloxicam increase the progression of the kidney disease more than not using meloxicam?
  76. Answer Me: In cats with refractory chronic gingivostomatitis, is administration of feline interferon omega more effective at reducing clinical signs than administration of prednisolone?
  77. Answered: In cats with permethrin intoxication is soybean oil-based IVLE therapy or olive oil-based (ClinOleic IVLE therapy) more effective in reducing time to recovery?
  78. Answer Me: Does a balanced electrolyte solution or 0.9% saline more efficacious when treating male cats with a urinary obstruction?
  79. Answer Me: In adult feline patients with chronic gingivostomatitis, does the combination of cyclosporine therapy and dental extractions compared to extractions alone lead to clinical improvement of oral lesions?
  80. Answer Me: In cats with mammary carcinomas undergoing surgical removal, does the addition of adjuvant chemotherapy increase the survival time, compared with surgery alone?
  81. Being Answered: In domestic cats in a shelter setting, does clicker training decrease behaviours associated with stress compared to no clicker training?
  82. Being Answered: In cats diagnosed with partial or complete cruciate rupture, does surgical intervention result in improved long-term function compared to medical management?
  83. Being Answered: In cats undergoing midline ovariohysterectomy, is the use of local infiltration anaesthesia with bupivacaine associated with a reduction in post-operative pain score?
  84. Being Answered: In male cats with urethral obstruction, does administration of prazosin compared with no administration of prazosin reduce the incidence of reoccurrence of urethral obstruction?
  85. Being Answered: In cats, does the presence of gastric Helicobacter spp., compared to their absence, increase the risk of developing gastritis?
  86. Being Answered: In cats does neutering versus non-neutering reduce the risk of mammary tumours?
  87. Being Answered: Is the use of symmetric dimethylarginine (SDMA) assay more sensitive in diagnosing chronic kidney disease in non-domestic captive felids, than serum creatinine measurements?
  88. Being Answered: In cats with IRIS stage III or IV chronic renal disease, does propofol co-induction with ketamine or midazolam reduce the risk of hypotension and oxidative red blood cell damage compared to induction with propofol as a sole agent?

General

  1. Answer Me: During sterile surgical procedures does wearing a disposable mask in theatre compared to not wearing any mask reduce the incidence of surgical site infections?
  2. Being Answered: In veterinary patients undergoing surgery does the use of a surgical safety checklist, compared to not using one, reduce the amount of perioperative errors?
  3. Answer Me: During venous catheter placement preparation, does the use of a mechanical scrub technique compared to a single wipe of the proposed area, reduce the incidence of catheter site infection?
  4. Answered: Pet ownership in the homeless population: do pets improve mental health status?
  5. Answered: In patients undergoing surgical preparation is the friction (back and forth method) compared to using concentric circles more effective in reducing infection (reduce CFU)?
  6. Answered: In small animal veterinary professionals, does implementation of an educational intervention, when compared to no intervention, improve hand hygiene compliance?
  7. Answer Me: In first opinion small animal veterinary consultations, does using a consultation communication framework increase client satisfaction?
  8. Answered: Is the TTA RAPID technique associated with more tibial diaphyseal fractures compared to traditional TTA?
  9. TBC
  10. TBC
  11. TBC
  12. Answered: Non-Clinical Benefits of Evidence Based Veterinary Medicine
  13. Answered: Does Physical Therapy after a TPLO Lead to Improvement of the 1-Year Postoperative Peak Vertical Force?
  14. Answered: Can I hang? Ideal time to replace IV fluids and sets to prevent fluid contamination and blood stream infection
  15. Answered: Choice of Suture Pattern for Linea Alba Closure
  16. Being Answered: In veterinary patients with peripheral intravenous catheters does catheter replacement every 72 hours compared to continuous maintenance reduce the risk of catheter associated infections?
  17. Answered: Does the use of disposable synthetic drapes as opposed to reusable woven drapes decrease the amount of surgical site infections in animals undergoing surgical procedures?
  18. Answer Me: In companion animal patients undergoing general anaesthesia, is insulating the extremities an effective means of maintaining core body temperature?
  19. Answer Me: During patient handovers, does the implementation of documentation or a standardised procedure improve the success of the handover process and patient welfare?
  20. Answered: Compared to in-person consultations, does telemedicine lead to similar levels of client and clinician satisfaction?

Production animal

  1. Answered: In dairy cow management do sand or composted bedding compared with rubber matting result in fewer disease incidence consequences?
  2. Answer Me: In dairy herds, does the annual use of live IBR vaccine protocols provide greater protection against the development of clinical disease compared to killed IBR vaccine protocols?
  3. Answer Me: In neonatal dairy calves, does navel disinfection at birth reduce the incidence of navel infections compared to no treatment of the navel?
  4. Answer Me: In neonatal lambs, does navel disinfection at birth reduce the incidence of navel infections compared to no treatment of the navel?
  5. Answer Me: In cows with foul in the foot, does topical antimicrobial therapy in addition to systemic antimicrobial therapy resolve the condition faster than systemic antimicrobials a lone.
  6. Being Answered: In the detection of pregnancy of cows 35 days and before, is the use of a pregnancy specific protein B blood test of similar sensitivity and specificity when compared to per rectal examination?
  7. Answered: In sheep exposed to caseous lyphadenitis what is the reduction in the risk of clinical disease in vaccinated sheep when compared to unvaccinated sheep?
  8. Being Answered: In calves undergoing disbudding with local anaesthetic, do NSAIDS administered at the time of the procedure reduce signs of post-operative pain compared to local anaesthetic alone?
  9. Being Answered: In lambs undergoing castration with rubber rings does administration of local anaesthetic reduce pain when compared to no local anaesthetic?
  10. Being Answered: In adult dairy cows with ovarian follicular cysts, does treatment with gonadotropin releasing hormone compared to human chorionic gonadotropin result in more rapid return to normal cyclicity?
  11. Answer Me: In cows with a left sided displaced abomasum, does a right sided approach to fixation compared to a left sided approach result in better long term productivity?
  12. Answer Me: In beef cattle affected with Actinobacillus lignieresii (woody tongue) does treatment with sodium iodide alone compared to sodium iodide plus oxytetracycline result in faster resolution of clinical signs?
  13. Answer Me: In post-parturient cows, with obturator nerve paralysis, does treatment with dexamethasone and flunixin meglumine result in faster return to function (weight bearing and ambulatory) than treatment with dexamethasone alone?
  14. Answer Me: In cattle with osteoarthritis do NSAIDs compared to glycosaminoglycans result in a greater decrease in  pain and lameness scores?
  15. Answered: In newborn piglets does drying versus no intervention reduce the risk of mortality pre-weaning?
  16. Answered: What is the evidence for intra-peritoneal fluid therapy of dehydration in neonatal calves?
  17. Answered: What are the performance and behavioural effects of separating dairy cows and their calves at birth?
  18. TBC
  19. Answered: Does heat stress affect immune function in dairy cows?
  20. Answered: In dairy cows with clinical mastitis do parenteral antibiotics in addition to intramammary antibiotics improve clinical cure rates compared to intramammary antibiotics only?
  21. Answered: What are the production effects of varying age at first calving in dairy cows?
  22. Answered: In auction market calves at high risk of developing BRD, does delayed (14-30 days) vaccination with a modified live respiratory pathogen vaccine (MLV) versus administration of MLV on-arrival (within 24 hours of arrival) to the feedlot, result in a decreased percentage of calves with BRD morbidity diagnosed based on visual signs and rectal temperature >40 degrees celsius?
  23. Answer Me: In piglets raised in indoor intensive housing, does two iron injections of 200 mg versus one 200 mg iron injection improve growth rates?
  24. Answer Me: In females of the bovine species, does vitamin E supplementation compared to no supplementation improve reproductive parameters?
  25. Answered: In calves undergoing castration without local anaesthetic, do NSAIDs administered either before, during or after the procedure reduce signs of post-operative pain?
  26. Answered: The effectiveness of oxytetracycline in the treatment of calves with contracted flexor tendonsIn [neonatal calves with contracted flexor tendons] is the use of a [three-day course of oxytetracycline in conjunction with other treatments] more effective in [returning the hoof to normal full weight bearing on both the toe and heel] compared to [no oxytetracycline]?
  27. Answered: In healthy lambs, does the administration of local anaesthetic reduce the pain response after castration and tail docking compared to the administration of meloxicam?
  28. Answered: In auction market calves at high risk of developing BRD, does delayed (14-30 days) vaccination with a modified live respiratory pathogen vaccine (MLV) versus administration of MLV on-arrival (within 24 hours of arrival) to the stocker operation, result in less calves with BRD morbidity diagnosed based on visual signs and rectal temperature >40 degrees Celsius, or less calves with BRD mortality?
  29. Being Answered: In intensively-farmed pigs, are there lower incidences of injuries from tail biting when enrichment is provided compared to no enrichment?
  30. Being Answered: In dairy cows with ketosis does treatment with glucocorticoids, as an adjunct to propylene glycol, compared with propylene glycol alone lead to better clinical outcomes?

Small animal

  1. Answered: In ferrets with adrenocortical disease, does treatment with deslorelin acetate compared to surgery result in a better prognosis?
  2. Answered: In rabbits displaying signs of anxiety/fear does the use of mirrors compared to no mirrors reduce the signs of anxiety/fear?
  3. Answered: In small animal surgery are alcoholic hand rubs superior than scrubbing brushes and antimicrobial soap at reducing bacterial counts?
  4. Answered: Comparison of 1mg/kg vs 0.2mg/kg of oral meloxicam for safe and effective analgesia in domestic rabbits
  5. Answered: In reducing surgical recovery time in rabbits, is twice daily administration of meloxicam more effective than a single daily dose?
  6. Being Answered: In rabbits undergoing general anesthesia does the use of v-gel result in superior outcomes when compared to other airway management devices?
  7. Being Answered: In rabbits with cheyletiellosis does topical selamectin or injectable ivermectin have better treatment efficacy?
  8. Being Answered: Is ultrasound or radiography more sensitive at detecting small intestinal obstructions in small animals?
  9. Answer Me: In guinea pigs, does feeding dicotyledonous green leaves (leafy greens) no more than once weekly compared to feeding leafy greens daily reduce the incidence of macroscopic urinary stones?
  10. Being Answered: In hospitalised cats and dogs, does regular flushing of an intravenous catheter with heparanised saline improve patency, in comparison to flushing with non-heparanised saline?
  11. Answer Me: Is creatinine more sensitive and specific than urea for diagnosing chronic renal disease in cats and dogs?
  12. Answer Me: In dogs and cats with dermatological disease, does the use of oral essential fatty acids compared to not using them reduce the clinical signs associated with the disease?
  13. Being Answered: In small animal surgery does the use of a forced air warming blanket during the intra operative phase compared to other active warming methods increase the risk of surgical site infections?
  14. Being Answered: In small animal anaesthesia, does the use of active and passive heating together during the perioperative stage, compared with using only active heating, reduce the incidence of hypothermia?
  15. Being Answered: In open fracture management of dogs and cats, does the use of peri and post operative antibacterial treatment, compared to only perioperative antibacterial treatment, reduce the likelihood of developing a post operative infection?
  16. Being Answered: In Otitis Externa in dogs and cats, does the use of in-house cytology before treatment compared with no in-house cytology, reduce the likelihood of relapse within a 6-month period?
  17. Being Answered: In dogs and cats with clinical toxoplasmosis, does pyrimethamine result in reduced time to clinical remission or reduced mortality compared with clindamycin?
  18. Answered: In domestic rabbits undergoing anaesthesia, how does the use of supraglottic airway devices compare to endotracheal intubation for ease of use in achieving a patent airway and maintaining a stable anaesthesia?
  19. Answer Me: In dogs and cats undergoing intravenous catheter placement does the use of chlorhexidine and alcohol have greater antimicrobial action than alcohol alone when used to prepare the intended catheter site?
  20. Being Answered: In lop-eared rabbits, does routine ear cleaning compared to no cleaning reduce the risk of aural diverticulosis?
  21. Being Answered: In dogs and cats undergoing hospitalisation, does intermittent flushing with heparinised saline improve central venous catheter patency compared with normal saline?
  22. Being Answered: Is tramadol hydrochloride alone effective in providing analgesia in rabbits?
  23. Being Answered: In dogs and cats receiving blood transfusions, does administration via gravity flow compared to infusion pump administration affect RBC survival time?
  24. Being Answered: In dogs and cats after orthopaedic or soft tissue surgery, does the peri-operative administration of injectable or oral metamizole (dipyrone) as opposed to no intervention result in lower post-operative pain scores or higher incidence of side effects?
  25. Being Answered: In dogs and cats, does a blood pressure measurement using doppler ultrasonography compared with direct arterial puncture results in similar blood pressure readings?