Is Alpha-casozepine Efficacious at Reducing Anxiety in Dogs?

Published:

2017-07-18

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DOI

https://doi.org/10.18849/ve.v2i3.67

Abstract

Clinical bottom line

There is currently no evidence to show that alpha-casozepine is effective as an anxiolytic when administered to dogs shortly (minutes to a few days) before exposure to an anxiety provoking stressor. There is limited and weak evidence to suggest that it may have a role to play in reducing anxiety in dogs over the medium to longer term but the available evidence is of low quality and / or high risk of bias, with confounding variables providing alternative explanations for the findings. More research is needed in this area.


Open Access Peer Reviewed

Author Biography

Louise Anne Buckley, Department of Animal Production, Welfare and Veterinary Sciences, Harper Adams University, Newport, Shropshire. TF10 8NB

Lecturer - Veterinary Nursing

References

Beata, C. et al. (2007) Effects of alpha-casozepine (Zylkene) versus selegiline hydrochloride (Selgian, Anipryl) on anxiety disorders in dogs. Journal of Veterinary Behaviour: Clinical Applications and Research, 2 (5), pp. 175-183 http://dx.doi.org/10.1016/j.jveb.2007.08.001

Kato, M. et al. (2012) Effects of prescription diet on dealing with stressful situations and performance of anxiety-related behaviors in privately owned anxious dogs. Journal of Veterinary Behavior: Clinical Applications and Research, 7 (1), pp. 21-26 http://dx.doi.org/10.1016/j.jveb.2011.05.025

Pageat, P. (1995) Pathologie du comportement du chien. Editions du Point Veterinaire, Maisons-Alfort: 208 – 224

Palestrini, C. et al (2010) Efficacy of a diet containing caseinate hydrolysate on signs of stress in dogs. Journal of Veterinary Behavior, 5 (6), pp. 309-317 http://dx.doi.org/10.1016/j.jveb.2010.04.004

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Vol. 2 No. 3 (2017): The third issue of 2017

Section: Knowledge Summaries

Categories :  Small Animal  /  Dogs  /  Cats  /  Rabbits  /  Production Animal  /  Cattle  /  Sheep  /  Pig  /  Equine  /  Exotics  /