The effect of pre-emptive incisional bupivacaine block on postoperative pain after coeliotomy in dogs

  • Kiriaki Pavlidou Anaesthesia and Intensive Care Unit, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 11th Stavrou Voutyra, 55236, Thessaloniki, Greece
  • Lysimachos G Papazoglou



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PICO question

Is there an effect on analgesia following coeliotomy in dogs after a block with local anaesthetics?


Clinical bottom line

Category of research question


The number and type of study designs reviewed

All the available evidence for this PICO question comes from clinical trials and one experimental/pharmacology study. All the studies were randomised; 5/7 were blinded clinical studies and 4/7 studies were prospective

Strength of evidence


Outcomes reported

It is not clear if the use of a local anaesthetic including bupivacaine or lidocaine as incisional blocks minimises the postoperative pain especially in the first 24 hours, as the results are not statistically significant between the groups


In conclusion, bupivacaine or lidocaine can minimise the postoperative pain but more clinical trials are needed


How to apply this evidence in practice

The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.

Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.


Open Access Peer Reviewed


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Carpenter, R., Wilson, D. & Evans, A. (2004). Evaluation of intraperitoneal and subcutaneous lidocaine and bupivacaine for analgesia following ovariohysterectomy in the dog. Veterinary Anaesthesia and Analgesia. 31(1), 46-52. DOI: 1111/j.1467-2995.2004.00137.x

Fitzpatrick, C. L., Weir, H. L. & Monnet, E. (2010). Effects of infiltration of the incision site with bupivacaine on postoperative pain and incisional healing in dogs undergoing ovariohysterectomy. Journal of the American Veterinary Medical Association. 237(4), 395–401. DOI:

McKune, C. M., Pascoe, P. J., Lascelles, B. D. X. & Kass, P. H. (2014). The challenge of evaluating pain and a pre-incisional local anesthetic block. PeerJ. 2(1), e341. DOI:

Morgaz, J., Muñoz-Rascón, P., Serrano-Rodríguez, J. M., Navarrete, R., Domínguez, J. M., Fernández-Sarmiento, J. A., Gómez-Villamandos, R. J., Serrano, J. M. & del Mar Granados, M. (2014). Effectiveness of pre-peritoneal continuous wound infusion with lidocaine for pain control following ovariohysterectomy in dogs. Veterinary Journal. 202(3), 522–526. DOI:

Savvas, I., Papazoglou, L. G., Kazakos, G., Anagnostou, T., Tsioli, V. & Raptopoulos, D. (2008). Incisional Block With Bupivacaine for Analgesia After Celiotomy in Dogs. Journal of the American Animal Hospital Association. 44(2), 60–66. DOI:

Wilson, D. V., Barnes, K. S. & Hauptman, J. G. (2004). Pharmacokinetics of combined intraperitoneal and incisional lidocaine in the dog following ovariohysterectomy. Journal of Veterinary Pharmacology and Therapeutics. 27(2), 105–109. DOI:





Vol. 6 No. 1 (2021): The first issue of 2021

Section: Knowledge Summaries

Categories :  Small Animal  /  Dogs  /  Cats  /  Rabbits  /  Production Animal  /  Cattle  /  Sheep  /  Pig  /  Equine  /  Exotics  /