There is an erratum to this paper published in Veterinary Evidence Vol 3, Issue 1 (2018): http://dx.doi.org/10.18849/ve.v3i1.168
Clinical bottom line
There is very weak veterinary clinical and experimental evidence based upon a limited number of studies to indicate that adding transdermal nitroglycerine to other therapies used for management of left-sided congestive heart failure in dogs speeds the resolution of clinical signs.
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McKie PM, Cataliotti A, Ichiki T, et al. (2014). M-atrial natriuretic peptide and nitroglycerin in a canine model of experimental acute hypertensive heart failure: differential actions of 2 cGMP activating therapeutics. Journal of the American Heart Association, 3(1):e000206. DOI: http://dx.doi.org/10.1161/JAHA.113.000206
Nakayama, T. Nishijima, Y. Miyamoto, et al. (2007). Effects of 4 classes of cardiovascular drugs on ventricular function in dogs with mitral regurgitation. Journal of Veterinary Internal Medicine, 21(3), pp. 445-450. PMID: 17552449 DOI: http://dx.doi.org/10.1111/j.1939-1676.2007.tb02988.x
Parameswaran, N. Hamlin, R. L. Nakayama, T. Rao, S. S. (1999). Increased splenic capacity in response to transdermal application of nitroglycerin in the dog. Journal of Veterinary Internal Medicine, 13(1), pp. 44-46. PMID: 10052063 DOI: 1111/j.1939-1676.1999.tb02164.x
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- Jenefer R Stillion, Søren R Boysen, Erratum to: Does Adding Transdermal Nitroglycerine to Other Therapies Used for Management of Left-sided Congestive Heart Failure in Dogs Speed the Resolution of Clinical Signs? , Veterinary Evidence: Vol. 3 No. 1 (2018): The first issue of 2018