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Does Adding Transdermal Nitroglycerine to Other Therapies Used for Management of Left-sided Congestive Heart Failure in Dogs Speed the Resolution of Clinical Signs?

Jenefer R Stillion, Søren R Boysen

Published:  12/12/2017    in:  Knowledge Summaries
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dog, viszla
Abstract

Clinical bottom line

There is very weak veterinary clinical and experimental evidence based upon a limited number of studies to indicate that adding transdermal nitroglycerine to other therapies used for management of left-sided congestive heart failure in dogs speeds the resolution of clinical signs.

 


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References

  1. Kanda A, Yoshida M, Kanou M, et al. (1995). Cardiovascular effects of NT-1, a new patch form of nitroglycerin, alone and in combination with nifedipine in conscious dogs. Journal of Pharmacy Pharmacology. 47(12A): pp. 1021-1024. DOI: http://dx.doi.org/10.1111/j.2042-7158.1995.tb03289.x

  2. McKie PM, Cataliotti A, Ichiki T, et al. (2014). M-atrial natriuretic peptide and nitroglycerin in a canine model of experimental acute hypertensive heart failure: differential actions of 2 cGMP activating therapeutics. Journal of the American Heart Association, 3(1):e000206. DOI: http://dx.doi.org/10.1161/JAHA.113.000206

  3. Nakayama, T. Nishijima, Y.  Miyamoto, et al. (2007). Effects of 4 classes of cardiovascular drugs on ventricular function in dogs with mitral regurgitation.   Journal of Veterinary Internal Medicine, 21(3), pp. 445-450. PMID: 17552449 DOI: http://dx.doi.org/10.1111/j.1939-1676.2007.tb02988.x

  4. Parameswaran, N. Hamlin, R. L.  Nakayama, T.  Rao, S. S. (1999). Increased splenic capacity in response to transdermal application of nitroglycerin in the dog.   Journal of Veterinary Internal Medicine, 13(1), pp. 44-46. PMID: 10052063 DOI: 1111/j.1939-1676.1999.tb02164.x

  5. Sellers R, Levy M, Amplatz K, Lillehei CW. Left retrograde cardioangiography in  acquired  cardiac  disease:  Technic,  indications  and  interpretations  in  700    Am J  Cardiol  1964;14: 437–447 DOI: http://dx.doi.org/10.1016/0002-9149(64)90027-X




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Copyright (c) 2017 Jenefer R Stillion, Søren R Boysen

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