Evidence Supporting Intralesional Stem Cell Therapy to Improve Equine Flexor Tendon Healing

  • Sushmitha Durgam Department of Veterinary Clinical Medicine University of Illinois 1008W Hazelwood Dr Urbana IL 61802
  • Matthew Stewart Department of Veterinary Clinical Medicine University of Illinois 1008W Hazelwood Dr Urbana IL 61802

Published:

2017-01-03

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DOI

https://doi.org/10.18849/ve.v2i1.50

Abstract

Clinical bottom line

Current experimental evidence suggests that intralesional stem cell administration improves the histological characteristics and matrix organisation of healing equine superficial digital flexor tendons (SDFT); however, the clinical relevance of these findings are not clear. Current case-based evidence suggests that cell-based therapies improve the quality of tendon healing and reduce the recurrence rates of SDFT injuries but the lack of any randomised, controlled prospective studies with function-based outcomes is still concerning, given the widespread advocacy for and use of ‘stem cell’ therapies for the treatment of equine tendon injuries.

 

Open Access Peer Reviewed

Author Biographies

Sushmitha Durgam, Department of Veterinary Clinical Medicine University of Illinois 1008W Hazelwood Dr Urbana IL 61802

Graduate student

Veterinary Clinical Medicine

Matthew Stewart, Department of Veterinary Clinical Medicine University of Illinois 1008W Hazelwood Dr Urbana IL 61802

Associate Professor

Veterinary Clinical Medicine

References

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Vol. 2 No. 1 (2017): The first issue of 2017

Section: Knowledge Summaries

Categories :  Small Animal  /  Dogs  /  Cats  /  Rabbits  /  Production Animal  /  Cattle  /  Sheep  /  Pig  /  Equine  /  Exotics  /