DOI
https://doi.org/10.18849/ve.v11i4.742Abstract
PICO Question
In bovines undergoing caesarean section does the use of synthetic absorbable uterine sutures compared with catgut result in less uterine tissue reactions?
Clinical bottom line
Category of research
Treatment.
Number and type of study designs reviewed
Three studies were critically appraised. Two were non-randomised controlled trials and one was a randomised controlled trial.
Strength of evidence
Weak.
Outcomes reported
One study found no difference in the incidence of uterine adhesions between plain catgut and polyglactin 910. Two other studies, which were both conducted on the same group of animals using chromic catgut and polyglycolic acid (PGA), demonstrated a lower incidence and severity of uterine adhesions, as well as reduced histopathological indicators of uterine tissue damage, with polyglycolic acid sutures compared to chromic catgut.
Conclusion
There is limited evidence concerning the difference in uterine tissue reactions caused when using catgut or a synthetic uterine suture material in bovine caesarean surgeries. The lack of comparability between the relevant studies in terms of population characteristics and type of suture material used (chromic and plain catgut) does not allow a clear conclusion to be made. In addition, uterine adhesion formation is likely to be multifactorial and there is no overall clear indication that the use of synthetic absorbable suture materials is superior in terms of reduced uterine tissue reactions. There are several other papers of interest which may provide further evidence, but these are not available in English and are therefore outside the scope of this Knowledge Summary.
References
Bakkum, E.A., Dalmeijer, R.A.J., Verdel, M.J.C., Hermans, J., Van Blitterswijk, C.A. & Trimbos, J.B. (1995). Quantitative analysis of the inflammatory reaction surrounding sutures commonly used in operative procedures and the relation to postsurgical adhesion formation. Biomaterials. 16(17), 1283–1289. DOI: https://doi.org/10.1016/0142-9612(95)91042-w
Biondo-Simões, M.D.L.P., Oda, M.H., Pasqual, S. & Robes, R.R. (2018). Comparative study of polyglactin 910 and simple catgut in the formation of intraperitoneal adhesions. Acta Cirúrgica Brasileira. 33(2), 102–109. DOI: https://doi.org/10.1590/s0102-865020180020000001
Bohy, A. (2001). Caesarean section in cows: should we regret the loss of catgut? Le Point Vétérinaire. 32(220), 62–65.
Boucoumont, D., Lecuyer, B., Rosentiehl, D., Tisserand, R., Troccon, B. & Oullier, R. (1979). Effect of caesarean section on fertility of cows. Comparative study of catgut and a polyglycolic acid thread. Le Point Vétérinaire. 8(36), 15–19.
Dhindsa, S.S., Dhaliwal, G.S., Ghuman, S.P.S. & Sood, N.K. (2010a). Alterations in uterine and peritoneal fluid cytology as well as uterine histopathology following caesarean operation with reference to suture material and intra-peritoneal lubricant in bovines. The Indian Journal of Animal Sciences. 80(6), 523–527. DOI: https://doi.org/10.56093/ijans.v80i6.35
Dhindsa, S.S., Dhaliwal, G.P.S. & Ghuman, S.P.S. (2010b). Prevention of uterine adhesion formation following caesarean section in bovines. The Indian Journal of Animal Sciences. 80(7), 626–628. DOI: https://doi.org/10.56093/ijans.v80i7.308
Gomes, M.E. & Reis, R.L. (2004). Biodegradable polymers and composites in biomedical applications: from catgut to tissue engineering. Part 1 Available systems and their properties. International Materials Reviews. 49(5), 261–273. DOI: https://doi.org/10.1179/095066004225021918
Kumar, D., Satish, & Purohit, G.N. (2022). Cesarean section in cattle: A review. Agricultural Reviews 43(2), 154–161. DOI: https://doi.org/10.18805/ag.r-1933
Langley-Hobbs, S.J. (2014). Sutures and general surgical implants. Elsevier eBooks. 105–116. DOI: https://doi.org/10.1016/b978-0-7020-4336-9.00010-x
Lyons, N.A., Karvountzis, S. & Knight-Jones, T.J.D. (2013). Aspects of bovine caesarean section associated with calf mortality, dam survival and subsequent fertility. The Veterinary Journal. 197(2), 342–350. DOI: https://doi.org/10.1016/j.tvjl.2013.01.010
Mijten, P., de Kruif, A., Van der Weyden, G.C. & Deluyker, H. (1997). Comparison of catgut and polyglactin 910 for uterine sutures during bovine caesarean sections. Veterinary Record. 140(17), 458–459. DOI: https://doi.org/10.1136/vr.140.17.458
Newman, K.D. & Anderson, D.E. (2005). Cesarean section in cows. Veterinary Clinics of North America: Food Animal Practice. 21(1), 73–100. DOI: https://doi.org/10.1016/j.cvfa.2004.12.001
Singh, S. & Maxwell, D. (2006). Tools of the trade. Best Practice & Research Clinical Obstetrics & Gynaecology. 20(1), 41–59. DOI: https://doi.org/10.1016/j.bpobgyn.2005.09.008
Zaag, E.V.D. & Klein, W.R. (1995). Suture materials and sutures for laparotomy incisions in horses and cattle. Tijdschrift voor Diergeneeskunde. 120(11), 324–330.
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