DOI
https://doi.org/10.18849/ve.v10i4.726Abstract
Question
In canine patients undergoing tibial plateau levelling osteotomy (TPLO) surgery for unilateral cranial cruciate ligament rupture (CCLR), is LLLT (low-level laser therapy (less than 200 mw)) treatment effective at reducing time to radiographic bone healing compared to no LLLT treatment?
The category of research question was:
Treatment.
The number and type of study designs that were critically appraised were:
Three studies (study 1: randomised, blinded, prospective clinical study, study 2: randomised, double blinded, placebo-controlled, parallel-group clinical trial and study 3: randomised controlled trial).
Critical appraisal of the selected papers meeting the inclusion criteria collectively provide zero/weak/moderate/strong evidence in terms of their experimental design and implementation:
Weak.
The outcomes reported are summarised as follows…
In all three studies the authors compared the use of LLLT to a control and concluded that LLLT treatment did not make a significant difference in improving radiographic bone healing. Therefore, the evidence which suggests LLLT improves radiographic bone healing in dogs recovering from TPLO surgery is weak.
In view of the strength of evidence and the outcomes from the studies the following conclusion is made…
There is a lack of conclusive evidence surrounding the use of LLLT treatment in dogs who underwent TPLO surgery. Based on current data it is difficult to say whether LLLT is beneficial and this demonstrates the requirement for further study to truthfully determine whether the laser device is effective for radiographic bone healing. One of three studies suggests that LLLT is beneficial to canine patients undergoing TPLO surgery for CCLR, radiographic bone healing in dogs was not the focus of that review.
References
Chavez, O.A., Renberg, W. & Cernicchiaro, N. (2024). Photobiomodulation therapy in dogs undergoing TPLO after cranial cruciate ligament rupture shows promise but no statistically significant difference in a randomized trial. American Journal of Veterinary Research. 85(2). DOI: https://doi.org/10.2460/ajvr.23.06.0138
Kennedy, K.C., Martinez, S.A., Martinez, S.E., Tucker, R.L. & Davies, N.M. (2018). Effects of low-level laser therapy on bone healing and signs of pain in dogs following tibial plateau levelling osteotomy. American Journal of Veterinary Research. 79(8), 893–904. DOI: https://doi.org/10.2460/ajvr.79.8.893
Renwick, S.M., Renwick, A.I., Brodbelt, D.C., Ferguson, J. & Abreu, H. (2018). Influence of class IV laser therapy on the outcomes of tibial plateau leveling osteotomy in dogs. Veterinary Surgery. 47(4), 507–515. DOI: https://doi.org/10.1111/vsu.12794
Rogatko, C., Baltzer, W. & Tennant, R. (2017). Preoperative low-level laser therapy in dogs undergoing tibial plateau levelling osteotomy: A blinded, prospective, randomized clinical trial. Veterinary and Comparative Orthopaedics and Traumatology. 30(01), 46–53. DOI: https://doi.org/10.3415/VCOT-15-12-0198
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