DOI
https://doi.org/10.18849/ve.v9i3.687Abstract
PICO Question
Does medical management of liver lobe torsion in rabbits reduce mortality compared with surgical intervention?
Clinical bottom line
Category of research
Treatment.
Number and type of study designs reviewed
Six studies were appraised in total. This consisted of three retrospective cohort studies and three case series.
Strength of evidence
Weak.
Outcomes reported
Medical management carries a similar 7-day survival rate compared to surgical treatment; however, long-term morbidity and mortality is increased compared with surgery. Delayed diagnosis and severe anaemia negatively affect outcomes of both groups.
Conclusion
Medical management does not reduce mortality compared with surgical treatment and within the literature there appears to be a preference for surgery when treating rabbits with liver lobe torsion.
How to apply this evidence in practice
The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.
Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
References
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Graham, J. E., Orcutt, C.J., Casale, S.A. & Basseches, J. (2014). Liver Lobe Torsion in Rabbits: 16 Cases (2007 to 2012)’ Journal of Exotic Pet Medicine. 23(3), 258–265. DOI: https://doi.org/10.1053/j.jepm.2014.06.010
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